Protein Details: Aquaporin-1

Protein ID

ICDB_Pro_0106

Protein Name

Aquaporin-1

Gene Name

AQY1; EC1118_1P2_5391g

Organism

Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Bakers yeast)

Length

327 amino acids

AlphaFoldDB

AF-C8ZJM1-F1-model_v4.pdb

Function

Water channel required to facilitate the transport of water across membranes. Involved in sporulation; freeze tolerance and osmotolerance. Is non-functional in most laboratory strains.

Sequence

MSSNDSNDTDKQHTRLDPTGVDDAYIPPEQPETKHHRFKISKDTLRNHFIAAAGEFCGTFMFLWCAYVICNVANHDVALVAAPDGSHPGQLIMIAIGFGFSVMFSIWCFAGVSGGALNPAVSLSLCLARAVSPTRCVVMWVSQIVAGMAAGGAASAMTPGEVLFANSLGLGCSRTRGLFLEMFGTAILCLTVLMTAVEKRETNFMAALPIGISLFIAHVALTAYTGTGVNPARSLGAAVAARYFPHYHWIYWIGPLLGSILAWSVWQLLQILDYTTYVTAEKAASTKEKAQKKVKPAVPLLWLKSNFSLLFFISRSLALNVIIFGKN

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

DOI ID

10.1073/pnas.0904673106